You can drop them early or free any time to break folks faces, and good free stuff is always good, but many in Commander might go with the 4/4 Wurms first in a Commander brew with 40 life to get too and trample too
Handling with Care Don't press them excessively
Any creature that gets sacrificed counts as having died , so sacrificing a creature will activate any when this dies triggers it might have
Its the ultimate Rule 0 card, and it even spots you the Panharmonicon effect if you want to go all in on party creatures
In terms of specific synergies with the new cards, there are a number of notables
Because of the Masques Rebel chain, the Sergeant%%%Ramosian Sergeant%%% can begin recruiting 2/2 Steadfast Guards and other recruits as soon as turn three, who in turn can beat down or get even larger Rebels