Ross (Eds.), *Modern Nutrition in Health and Disease* (9th ed., pp
Recent cardiovascular outcome trials involving GLP-1 receptor agonists, especially liraglutide and semaglutide, have shown a significant reduction in major adverse cardiovascular events (MACE) among patients with type 2 diabetes at high risk for cardiovascular disease (14, 36)
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Nevertheless, caution is warranted in individuals with diabetes or those at risk of hypoglycaemia, particularly if they are also taking insulin or a sulfonylurea
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However, the authors concluded that more studies are needed to better understand whether supplementing with calcium alone is effective for GLP-1 secretion, or if the effects only occur when its combined with other nutrients