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Its binding to GHS (ghrelin) receptors is believed to induce GH release with high specificity and minimal impact on other hormonal systems
Therapeutically, these cells can be further potentiated using agents that intensify iron release (e.g., NCOA4 activators), enhance ACSL4-mediated PUFA incorporation, or inhibit GPX4-stabilizing pathways (106)
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That profile could be attractive for patients who cannot tolerate benzodiazepines or Z-drugs, though published clinical trial data remains limited
Fatty liver is the most common liver disorder today
doi: 10.3390/ijms22094642 130 SchmidtHMKelleyEEStraubAC
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