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Using kidney stone as a negative control outcome, there was no significant difference in the risk of kidney stone between GLP-1RA compared with DPP4i (HR, 0.99

Unlike stimulant-based weight loss medications, GLP-1 and dual GIP/GLP-1 agonists do not function primarily as metabolic stimulants or thermogenic agents

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If nausea persists or worsens, particularly if accompanied by vomiting that prevents adequate hydration or nutrition for more than 24 hours, contact your healthcare provider promptly

These drugs slow digestion, which makes these problems worse