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A larger gauge needle (18 to 21 gauge) works well for this step

Acknowledgements This work was funded by the DFG grant DE 1431/20-1 to M.D

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Tirzepatide is administered as a once-weekly subcutaneous injection, with dosing typically initiated at 2.5 mg and increased by 2.5 mg every 4 weeks up to a maintenance dose of 5-15 mg based on tolerability and therapeutic response

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