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Improving the supply of raw materials for GSH systems The direct administration of GSH in vivo is probably an obvious way to increase GSH It has been demonstrated that modified oral glutathione-like liposomal GSH increases erythrocyte and plasma GSH levels and reduces oxidative stress biomarkers [98]
The incretin group of hormones influences several metabolic processes, including glucose uptake in adipose tissue and muscle, enhanced insulin biosynthesis and secretion via efficient GI glucose sensing, suppression of glucagon secretion, increased lipolysis and fatty acid synthesis in adipose tissue, and reduced hepatic gluconeogenesis 53
10 NUTRITIONAL SUPPLEMENTS AND METABOLIC SYNDROME
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Eli Lilly has created tirzepatide (Zepbound), which incorporates the activity of another incretin-like peptide, GIP, into the GLP-1 framework [22]