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This observation may be due to inclusion of younger patients with more severe degree of obesity at baseline, and longer follow-up in the obesity trial compared with the diabetes trial (Table 1)
The Lancet , 399(10326), 2192-2203
Here, in this randomized, double-blind, placebo-controlled trial, participants ( n = 98) were randomly assigned to 48 weeks of once-weekly subcutaneous retatrutide (1, 4, 8 or 12 mg dose) or placebo
Yue X, et al
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